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Article

Polymorphisms in COX-2 gene influence prostate cancer susceptibility in a northern Indian cohort.

Archives of medical research - 1 Oct 2011

Mandal Raju K, Mittal Rama D

Abstract excerpt

BACKGROUND AND AIMS: Cyclooxygenase-2 (COX-2) converts arachidonic acid to prostaglandins, which are important mediators of cell proliferation and inflammation. Evidence indicates that COX-2 plays a role in carcinogenesis and that it is overexpressed in prostate tumors. We examined whether sequence variants in the COX-2 gene were associated with prostate cancer (PCa) risk. METHODS: In a hospital-based...

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Source

Identifiers

PMID: 22023987
DOI: 10.1016/j.arcmed.2011.10.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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