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Article

Exploratory study of a KLK2 polymorphism as a prognostic marker in prostate cancer.

Cancer biomarkers : section A of Disease markers - 1 Jan 2010

Kohli Manish, Rothberg Paul G, Feng Changyong, Messing Edward, Joseph Jean, Rao Sreevidya Sadasiva, Hendershot Allison, Sahsrabudhe Deepak

Abstract excerpt

OBJECTIVES: An association of a single nucleotide polymorphism (SNP) of the KLK2 gene (rs198977; c.748C>T; R250W) with risk for developing prostate cancer has been observed. We evaluated the role of R250W SNP for prognosis in prostate cancer. METHODS: The c.748C>T SNP was genotyped from blood DNA of 182 patients after completing initial cancer treatments. For evaluating prognosis of genotype groups, associations...

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Source

Open in PubMed Open full text

Identifiers

PMID: 21178268
DOI: 10.3233/CBM-2010-0152
PMCID: PMC3982319

Genes

KLK2

Variants

rs198977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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