Article
The association between MMP2 -1306 C > T (rs243865) polymorphism and risk of prostate cancer.
Irish journal of medical science - 1 Feb 2017
Shajarehpoor Salavati L, Tafvizi F, Manjili H K
Abstract excerpt
BACKGROUND: Prostate cancer is the second most common cancer in men. Matrix metalloproteinase-2 (MMP2) is the most important member of the matrix metalloproteinase family. MMP2 digests the basement membrane and causes changes in the extracellular matrix which in turn facilitate cancer invasion. It, therefore, has a major role in tumor angiogenesis. Previous studies have identified a single-nucleotide polymorphism...
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