Article
The Maestro (Mro) gene is dispensable for normal sexual development and fertility in mice.
PloS one - 1 Jan 2008
Smith Lee, Willan John, Warr Nick, Brook Frances A, Cheeseman Michael, Sharpe Richard, Siggers Pam, Greenfield Andy
Abstract excerpt
The mammalian gonad arises as a bipotential primordium from which a testis or ovary develops depending on the chromosomal sex of the individual. We have previously used DNA microarrays to screen for novel genes controlling the developmental fate of the indifferent embryonic mouse gonad. Maestro (Mro), which encodes a HEAT-repeat protein, was originally identified as a gene exhibiting sexually dimorphic expression...
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