Article
Nitric oxide accumulation is required to protect against iron-mediated oxidative stress in frataxin-deficient Arabidopsis plants.
FEBS letters - 4 Feb 2009
Martin Mariana, Colman María José Rodríguez, Gómez-Casati Diego F, Lamattina Lorenzo, Zabaleta Eduardo Julián
Abstract excerpt
Frataxin is a mitochondrial protein that is conserved throughout evolution. In yeast and mammals, frataxin is essential for cellular iron (Fe) homeostasis and survival during oxidative stress. In plants, frataxin deficiency causes increased reactive oxygen species (ROS) production and high sensitivity to oxidative stress. In this work we show that a knock-down T-DNA frataxin-deficient mutant of Arabidopsis...
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