Article
Deficiency of Arabidopsis thaliana frataxin alters activity of mitochondrial Fe-S proteins and induces oxidative stress.
The Plant journal : for cell and molecular biology - 1 Dec 2006
Busi Maria V, Maliandi María V, Valdez Hugo, Clemente Marina, Zabaleta Eduardo J, Araya Alejandro, Gomez-Casati Diego F
Abstract excerpt
Frataxin, a protein crucial for the biogenesis of mitochondria in different organisms, was recently identified in Arabidopsis thaliana. To investigate the role of frataxin in higher plants, we analyze two knock-out and one knock-down T-DNA insertion mutants. The knock-out mutants present an embryo-lethal phenotype, indicating an essential role for frataxin. The knock-down mutant has reduced frataxin mRNA and...
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