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Article

Competition between reversible aggregation and loop formation in denatured iso-1-cytochrome c.

Biochemistry - 20 Jan 2009

Tzul Franco O, Kurchan Eydiejo, Roder Heinrich, Bowler Bruce E

Abstract excerpt

The competition between intramolecular histidine-heme loop formation and ligand-mediated oligomer formation in the denatured state is investigated for two yeast iso-1-cytochrome c variants, AcH26I52 and AcA25H26I52. Besides the native His 18 heme ligand, both variants contain a single His at position 26. The AcA25H26I52 variant has Pro 25 mutated to Ala. The concentration dependence of the apparent pK(a) for His...

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Identifiers

PMID: 19113858
DOI: 10.1021/bi801977j
PMCID: PMC2645900

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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