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Chaperoning erythropoiesis

25 Dec 2008

Abstract excerpt

Multisubunit complexes containing molecular chaperones regulate protein production, stability, and degradation in virtually every cell type. We are beginning to recognize how generalized and tissue-specific chaperones regulate specialized aspects of erythropoiesis. For example, chaperones intersect with erythropoietin signaling pathways to protect erythroid precursors against apoptosis. Molecular chaperones also...

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Identifiers

PMID: 19109556
DOI: 10.1182/blood-2008-09-115238

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