Article
Association between the PTPN22 1858C/T gene polymorphism and tuberculosis resistance.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2013
Boechat Antonio Luiz, Ogusku Mauricio Morishi, Sadahiro Aya, dos Santos Maria Cristina
Abstract excerpt
Previous studies identified the functional polymorphism 1858C/T in the gene PTPN22 in association with several autoimmune diseases and with resistance to tuberculosis (TB). This study is the first to investigate the association between pulmonary TB and the PTPN22 1858C/T polymorphism in the Brazilian Amazon. We conducted a case-control study involving a group of 413 individuals, comprised of 208TB carriers and...
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