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Article

Integrative genomic identification of genes on 8p associated with hepatocellular carcinoma progression and patient survival.

Gastroenterology - 1 Apr 2012

Roessler Stephanie, Long Ezhou Lori, Budhu Anuradha, Chen Yidong, Zhao Xuelian, Ji Junfang, Walker Robert, Jia Hu-Liang, Ye Qing-Hai, Qin Lun-Xiu, Tang Zhao-You, He Ping, Hunter Kent W, Thorgeirsson Snorri S, Meltzer Paul S, Wang Xin Wei

Abstract excerpt

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is an aggressive malignancy; its mechanisms of development and progression are poorly understood. We used an integrative approach to identify HCC driver genes, defined as genes whose copy numbers associate with gene expression and cancer progression. METHODS: We combined data from high-resolution, array-based comparative genomic hybridization and transcriptome...

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Source

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Identifiers

PMID: 22202459
DOI: 10.1053/j.gastro.2011.12.039
PMCID: PMC3321110

Genes

DLC1
SORBS3
CCDC25
ELP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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