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Article

Preclinical evaluation of GS-9160, a novel inhibitor of human immunodeficiency virus type 1 integrase.

Antimicrobial agents and chemotherapy - 1 Mar 2009

Jones Gregg S, Yu Fang, Zeynalzadegan Ameneh, Hesselgesser Joseph, Chen Xiaowu, Chen James, Jin Haolun, Kim Choung U, Wright Matthew, Geleziunas Romas, Tsiang Manuel

Abstract excerpt

GS-9160 is a novel and potent inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase (IN) that specifically targets the process of strand transfer. It is an authentic inhibitor of HIV-1 integration, since treatment of infected cells results in an elevation of two-long terminal repeat circles and a decrease of integration junctions. GS-9160 has potent and selective antiviral activity in primary human T...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19104010
DOI: 10.1128/AAC.00984-08
PMCID: PMC2650545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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