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Article

Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs.

Viruses - 29 Jan 2021

Smith Steven J, Zhao Xue Zhi, Passos Dario Oliveira, Lyumkis Dmitry, Burke Terrence R, Hughes Stephen H

Abstract excerpt

Integrase strand transfer inhibitors (INSTIs) are currently recommended for the first line treatment of human immunodeficiency virus type one (HIV-1) infection. The first-generation INSTIs are effective but can select for resistant viruses. Recent advances have led to several potent second-generation INSTIs that are effective against both wild-type (WT) HIV-1 integrase and many of the first-generation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33572956
DOI: 10.3390/v13020205
PMCID: PMC7912079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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