Article
Predicted gene sequence C10orf112 is transcribed, exhibits tissue-specific expression, and may correspond to AD7.
Genomics - 1 Apr 2009
Zubenko George S, Hughes Hugh B
Abstract excerpt
Case-control and prospective longitudinal studies have revealed an interaction of the anonymous D10S1423 234 bp allele with the APOE4 allele in determining the age-specific risk of Alzheimer's disease (AD). The D10S1423 polymorphism resides within intron 10 of open reading frame C10orf112, whose predicted product resembles a low-density lipoprotein receptor (NCBI Build 35.1). These observations suggest that the...
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