Article
No evidence of association between the D10S1423 locus and Alzheimer disease in Brazilian patients.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2001
Nishimura A L, Oliveira J R, Otto P A, Matioli S R, Brito-Marques P R, Bahia V S, Nitrini R, Zatz M
Abstract excerpt
In a genome survey for Alzheimer's disease (AD), Zubenko et al. (1998) reported that the 234bp allele of the D10S1423 locus was more frequent among AD cases than in controls. We have analyzed this polymorphic locus in patients and healthy controls and observed that the 226bp allele is the most frequent allele in the D10S1423 locus in Brazilian AD patients. However, no statistically significant association between...
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