Article
MicroRNAs in kidney disease: an emerging understanding.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 May 2013
Khella Heba W Z, Bakhet Marize, Lichner Zsuzsanna, Romaschin Alexander D, Jewett Michael A S, Yousef George M
Abstract excerpt
MicroRNAs (miRNAs) are short noncoding RNA molecules that function by negatively regulating the expression of their target genes in a tightly controlled manner. Accumulating evidence, based in part on effects seen after miRNA overexpression and/or knockdown, points to the critical involvement of miRNAs in kidney function in health and disease. In this review, we provide a quick overview of the biogenesis of...
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