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Article

Integrative microRNA-gene expression network analysis in genetic hypercalciuric stone-forming rat kidney

31 Mar 2016

Abstract excerpt

Background. MicroRNAs (miRNAs) influence a variety of biological functions by regulating gene expression post-transcriptionally. Aberrant miRNA expression has been associated with many human diseases. Urolithiasis is a common disease, and idiopathic hypercalciuria (IH) is an important risk factor for calcium urolithiasis. However, miRNA expression patterns and their biological functions in urolithiasis remain...

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PMID: 27069814
DOI: 10.7717/peerj.1884

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