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Article

Quantitative monitoring of NPM1 mutations provides a valid minimal residual disease parameter following allogeneic stem cell transplantation.

Experimental hematology - 1 Jan 2009

Bacher Ulrike, Badbaran Anita, Fehse Boris, Zabelina Tatjana, Zander Axel Rolf, Kröger Nicolaus

Abstract excerpt

BACKGROUND: Minimal residual disease (MRD) diagnostics in acute myeloid leukemia (AML) gain increasing importance after allogeneic stem cell transplantation (SCT). Nucleophosmin (NPM1) mutations, with their high frequency in AML, were suggested to represent suitable MRD markers, but so far no study has evaluated their usefulness in the posttransplantation period. MATERIALS AND METHODS: We evaluated the validity...

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Share to Monitoring, Physiologic
Share to Neoplasm, Residual

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19100523
DOI: 10.1016/j.exphem.2008.09.014

Genes

SCT
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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