Article
Minimal residual disease diagnostics in patients with acute myeloid leukemia in the post-transplant period: comparison of peripheral blood and bone marrow analysis.
Leukemia & lymphoma - 1 Oct 2010
Stahl Tanja, Badbaran Anita, Kröger Nicolaus, Klyuchnikov Evgeny, Zabelina Tatjana, Zeschke Silke, Schafhausen Philippe, Schultz Waltraud, Asenova Svetlana, Smirnova Anna, Wolschke Christine, Ayuk Francis, Zander Axel R, Fehse Boris, Bacher Ulrike
Abstract excerpt
Considering the high relapse rates of AML after allogeneic hematopoietic stem cell transplant, research aims to improve post-transplant surveillance. To determine the value of peripheral blood (PB) for post-transplant minimal residual disease monitoring, we compared 38 PB and bone marrow (BM) sample pairs in 25 stem cell recipients with NPM1-mutated AML (12 males, 13 females, ages 21-73 years). NPM1A mutation...
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