Article
Positional analyses of BRCA1-dependent expression in Saccharomyces cerevisiae.
Cell cycle (Georgetown, Tex.) - 15 Dec 2008
Skibbens Robert V, Ringhoff Danielle N, Marzillier Jutta, Cassimeris Lynne, Eastman Laura
Abstract excerpt
Mutations in BRCA1 account for a significant proportion of hereditary breast and ovarian cancers, but analysis of BRCA1 function is complicated by pleiotropic effects and binding partners (Pol II holoenzyme and transcription factors, chromatin remodelers, recombination complexes and E3 ligases)....
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