Article
Genetic dissection of transcriptional regulation in budding yeast.
Science (New York, N.Y.) - 26 Apr 2002
Brem Rachel B, Yvert Gaël, Clinton Rebecca, Kruglyak Leonid
Abstract excerpt
To begin to understand the genetic architecture of natural variation in gene expression, we carried out genetic linkage analysis of genomewide expression patterns in a cross between a laboratory strain and a wild strain of Saccharomyces cerevisiae. Over 1500 genes were differentially expressed between the parent strains. Expression levels of 570 genes were linked to one or more different loci, with most...
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