Article
ksgA mutations confer resistance to kasugamycin in Neisseria gonorrhoeae.
International journal of antimicrobial agents - 1 Apr 2009
Duffin Paul M, Seifert H Steven
Abstract excerpt
The aminoglycoside antibiotic kasugamycin (KSG) inhibits translation initiation and thus the growth of many bacteria. In this study, we tested the susceptibilities to KSG of 22 low-passage clinical isolates and 2 laboratory strains of Neisseria gonorrhoeae. Although the range of KSG minimum inhibitory concentrations (MICs) was narrow (seven-fold), clinical isolates and laboratory strains fell into three distinct...
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