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Article

Mutations causing in vitro resistance to azithromycin in Neisseria gonorrhoeae.

International journal of antimicrobial agents - 1 May 2003

Johnson Steven R, Sandul Amy L, Parekh Manhar, Wang Susan A, Knapp Joan S, Trees David L

Abstract excerpt

In 1999, a cluster of gonococcal isolates exhibiting high Minimal Inhibitory Concentrations (MICs), to azithromycin (2.0-4.0 mg/l) were identified in Kansas City, MO. Isolates were characterized by auxotype/serovar class, lipoprotein (Lip) subtyping and sequencing of the mtrR gene, which has been implicated in decreased azithromycin susceptibility in the gonococcus. Isolates were Pro/IB-3 and contained the 17c...

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Identifiers

PMID: 12727073
DOI: 10.1016/s0924-8579(03)00039-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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