Article
Genetic recombination in Streptomyces michiganensis DSM 40,015 revealed three genes responsible for the formation of melanin.
Journal of basic microbiology - 1 Jan 1991
Held T, Kutzner H J
Abstract excerpt
By UV and NTG mutagenesis numerous auxotrophic, antibiotic-resistant and melanin-negative mutants were isolated from Streptomyces michiganensis DSM 40,015 which proved to possess a efficient photoreactivation system. Using a mel- test strain with three auxotrophic markers and a antibiotic resistance for crosses with numerous prototrophic mel- strains three classes of mutants (melA, melB and melC) could be found....
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