Article
Genetic analysis of the phosphinothricin-tripeptide biosynthetic pathway of Streptomyces viridochromogenes Tü494.
Applied microbiology and biotechnology - 1 Mar 1991
Alijah R, Dorendorf J, Talay S, Pühler A, Wohlleben W
Abstract excerpt
Streptomyces viridochromogenes Tü494 produces the antibiotic phosphinothricyl-alanyl-alanine (Ptt). Ptt-non-producing mutants were isolated following N-methyl-N'-nitro-N-nitrosoguanidine (NTG) or UV light treatment of spore suspensions. In co-synthesis and bioconversion experiments the mutational...
Topics
- Anti-Bacterial Agents
- Cosmids
- DNA, Bacterial
- Drug Resistance, Microbial
- Genetic Complementation Test
- Genomic Library
- Mutation
- Organophosphorus Compounds
- Restriction Mapping
- Spores, Bacterial
- Streptomyces
- Ultraviolet Rays
