Article
Genetic analysis of the phosphinothricin-tripeptide biosynthetic pathway of Streptomyces viridochromogenes Tü494.
Applied microbiology and biotechnology - 1 Mar 1991
Alijah R, Dorendorf J, Talay S, Pühler A, Wohlleben W
Abstract excerpt
Streptomyces viridochromogenes Tü494 produces the antibiotic phosphinothricyl-alanyl-alanine (Ptt). Ptt-non-producing mutants were isolated following N-methyl-N'-nitro-N-nitrosoguanidine (NTG) or UV light treatment of spore suspensions. In co-synthesis and bioconversion experiments the mutational blocks in the biosynthetic pathway were localized. The mutant NTG1 was analysed in detail. This mutant acts as a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
