Characterization of mutants defective in melanogenesis and a gene for tyrosinase of Streptomyces griseus.

doi:10.7164/antibiotics.54.789

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Characterization of mutants defective in melanogenesis and a gene for tyrosinase of Streptomyces griseus.

The Journal of antibiotics - 1 Oct 2001

Endo K, Kamo K, Hosono K, Beppu T, Ueda K

Abstract excerpt

Nitrosoguanidine-induced melanin-negative mutants of Streptomyces griseus were classified according to their ability to produce streptomycin and A-factor, and to form aerial mycelium. A large proportion of the mutants showed deficiency in either antibiotic production and morphological development or both, suggesting close regulatory correlation between melanogenesis and morphological and physiological...

Topics

4-Butyrolactone
Amino Acid Sequence
Anti-Bacterial Agents
Cell Differentiation
Cloning, Molecular
DNA, Fungal
Melanins
Molecular Sequence Data
Monophenol Monooxygenase
Mutagenesis
Mutagens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nitrosoguanidines

Open Reading Frames

Phenotype

Plasmids

Reverse Transcriptase Polymerase Chain Reaction

Streptomyces griseus

Source

Open in PubMed

Identifiers

PMID: 11776433
DOI: 10.7164/antibiotics.54.789

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of mutants defective in melanogenesis and a gene for tyrosinase of Streptomyces griseus.PMID 11776433Read ↗

Melanin production in Escherichia coli from a cloned tyrosinase gene.Semantic proximity Read ↗

Genetic recombination in Streptomyces michiganensis DSM 40,015 revealed three genes responsible for the formation of melanin.Semantic proximity Read ↗

Secretion of the Streptomyces tyrosinase is mediated through its trans-activator protein, MelC1.Semantic proximity Read ↗

Isolation and characterisation of Gaeumannomyces graminis var. graminis melanin mutants.Semantic proximity Read ↗

Identification of a Gene Involved in the Negative Regulation of Pyomelanin Production in Ralstonia solanacearum.Semantic proximity Read ↗

Identification of an operon involved in tyrosinase activity and melanin synthesis in Marinomonas mediterranea.Semantic proximity Read ↗

A cloned ompR-like gene of Streptomyces lividans 66 suppresses defective melC1, a putative copper-transfer gene.Semantic proximity Read ↗

Melanization of a meristematic mutant of Fonsecaea monophora increases tolerance to stress factors while no effects on antifungal susceptibility.Semantic proximity Read ↗

NsdD, a GATA-type transcription factor is involved in regulation and biosynthesis of macromolecules melanin, pullulan, and polymalate in Aureobasidium melanogenum.Semantic proximity Read ↗

Mechanism of the incidental production of a melanin-like pigment during 6-demethylchlortetracycline production in Streptomyces aureofaciens.Semantic proximity Read ↗

[Genetic determination of tyrosinase synthesis and melanogenesis in microorganisms].Semantic proximity Read ↗

Melanin-deficient mutants of<i>Cryptococcus neoformans</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.