Article
Characterization of mutants defective in melanogenesis and a gene for tyrosinase of Streptomyces griseus.
The Journal of antibiotics - 1 Oct 2001
Endo K, Kamo K, Hosono K, Beppu T, Ueda K
Abstract excerpt
Nitrosoguanidine-induced melanin-negative mutants of Streptomyces griseus were classified according to their ability to produce streptomycin and A-factor, and to form aerial mycelium. A large proportion of the mutants showed deficiency in either antibiotic production and morphological development or both, suggesting close regulatory correlation between melanogenesis and morphological and physiological...
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