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Article

The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations.

European heart journal - 1 Jul 2009

Jensen Majken K, Rimm Eric B, Mukamal Kenneth J, Edmondson Andrew C, Rader Daniel J, Vogel Ulla, Tjønneland Anne, Sørensen Thorkild I A, Schmidt Erik B, Overvad Kim

Abstract excerpt

AIMS: Endothelial lipase (LIPG) is implicated in the metabolism of high-density lipoprotein cholesterol (HDL-C). Small studies in selected populations have reported higher HDL-C levels among carriers of the common T111I variant in LIPG, but whether this variant is associated with plasma lipids and risk of coronary heart disease (CHD) in the general population is unclear. The objective of this study was to address...

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Identifiers

PMID: 19411665
DOI: 10.1093/eurheartj/ehp145
PMCID: PMC2733737

Genes

LIPG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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