Article
The meiosis-specific Cdc20 family-member Ama1 promotes binding of the Ssp2 activator to the Smk1 MAP kinase.
Molecular biology of the cell - 1 Jan 2018
Omerza Gregory, Tio Chong Wai, Philips Timothy, Diamond Aviva, Neiman Aaron M, Winter Edward
Abstract excerpt
Smk1 is a meiosis-specific MAP kinase (MAPK) in budding yeast that is required for spore formation. It is localized to prospore membranes (PSMs), the structures that engulf haploid cells during meiosis II (MII). Similar to canonically activated MAPKs, Smk1 is controlled by phosphorylation of its activation-loop threonine (T) and tyrosine (Y). However, activation loop phosphorylation occurs via a noncanonical...
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