Article
Normal mitochondrial respiratory function is essential for spatial remote memory in mice.
Molecular brain - 16 Dec 2008
Tanaka Daisuke, Nakada Kazuto, Takao Keizo, Ogasawara Emi, Kasahara Atsuko, Sato Akitsugu, Yonekawa Hiromichi, Miyakawa Tsuyoshi, Hayashi Jun-Ichi
Abstract excerpt
BACKGROUND: Mitochondrial DNA (mtDNA) with pathogenic mutations has been found in patients with cognitive disorders. However, little is known about whether pathogenic mtDNA mutations and the resultant mitochondrial respiration deficiencies contribute to the expression of cognitive alterations, su...
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