Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells.

Histochemistry and cell biology - 1 Mar 2009

Son Seiichi, Kojima Takashi, Decaens Catherine, Yamaguchi Hiroshi, Ito Tatsuya, Imamura Masafumi, Murata Masaki, Tanaka Satoshi, Chiba Hideki, Hirata Koichi, Sawada Norimasa

Abstract excerpt

The polarization of hepatocytes involves formation of functionally distinct sinusoidal (basolateral) and bile canalicular (apical) plasma membrane domains that are separated by tight junctions. Although various molecular mechanisms and signaling cascades including polarity complex proteins may contribute to bile canalicular formation in hepatocytes, the role of tight junction proteins in bile canalicular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Hybrid Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Phenotype

Share to RNA, Small Interfering

Share to Up-Regulation

Source

Identifiers

PMID: 19084987
DOI: 10.1007/s00418-008-0546-0

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells.PMID 19084987Read ↗

Structural and functional hepatocyte polarity and liver disease.Semantic proximity Read ↗

Hepatocyte polarity.Semantic proximity Read ↗

Protective Functions of ZO-2/Tjp2 Expressed in Hepatocytes and Cholangiocytes Against Liver Injury and Cholestasis.Semantic proximity Read ↗

Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiencySemantic proximity Read ↗

Protective functions of ZO-2/Tjp2 expressed in hepatocytes and cholangiocytes against liver injury and cholestasisSemantic proximity Read ↗

The unique polarity phenotype of hepatocytes.Semantic proximity Read ↗

Establishment of hepatic cell polarity in the rat hepatoma-human fibroblast hybrid WIF-B9. A biphasic phenomenon going from a simple epithelial polarized phenotype to an hepatic polarized one.Semantic proximity Read ↗

Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b.Semantic proximity Read ↗

In vitro differentiation of WB-F344 rat liver epithelial cells into the biliary lineage.Semantic proximity Read ↗

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.Semantic proximity Read ↗

The structural and functional polarity of the hepatic human/rat hybrid WIF-B is a stable and dominant trait.Semantic proximity Read ↗

Cell polarity development and protein trafficking in hepatocytes lacking E-cadherin/beta-catenin-based adherens junctions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.