Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

"Off-on" electrochemical hairpin-DNA-based genosensor for cancer diagnostics.

Analytical chemistry - 1 Mar 2011

Farjami Elaheh, Clima Lilia, Gothelf Kurt, Ferapontova Elena E

Abstract excerpt

A simple and robust "off-on" signaling genosensor platform with improved selectivity for single-nucleotide polymorphism (SNP) detection based on the electronic DNA hairpin molecular beacons has been developed. The DNA beacons were immobilized onto gold electrodes in their folded states through the alkanethiol linker at the 3'-end, while the 5'-end was labeled with a methylene blue (MB) redox probe. A typical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrochemical Techniques

Share to Neoplasms

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 21314139
DOI: 10.1021/ac1032929

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

"Off-on" electrochemical hairpin-DNA-based genosensor for cancer diagnostics.PMID 21314139Read ↗

Picomolar sensitive and SNP-selective "Off-On" hairpin genosensor based on structure-tunable redox indicator signals.Semantic proximity Read ↗

Electroanalysis of single-nucleotide polymorphism by hairpin DNA architectures.Semantic proximity Read ↗

Electrochemical biosensors employing an internal electrode attachment site and achieving reversible, high gain detection of specific nucleic acid sequences.Semantic proximity Read ↗

Single-nucleotide polymorphism detection with "wire-like" DNA probes that display quasi "on-off" digital action.Semantic proximity Read ↗

Detection of single-nucleotide polymorphisms using an ON-OFF switching of regenerated biosensor based on a locked nucleic acid-integrated and toehold-mediated strand displacement reaction.Semantic proximity Read ↗

Sensitive Electrochemical Biosensor for Rapid Screening of Tumor Biomarker TP53 Gene Mutation Hotspot.Semantic proximity Read ↗

In situ, digital-like, and reagentless discrimination of label-free SNPs of 90-mer length with easily synthesized electrochemical DNA probes.Semantic proximity Read ↗

Graphene platform for hairpin-DNA-based impedimetric genosensing.Semantic proximity Read ↗

Multiplexed electrochemical DNA sensor for single-nucleotide polymorphism typing by using oligonucleotide-incorporated nonfouling surfaces.Semantic proximity Read ↗

Electronic detection of nucleic acids: a versatile platform for molecular diagnostics.Semantic proximity Read ↗

Improving the sensitivity and selectivity of a DNA probe using graphene oxide-protected and T7 exonuclease-assisted signal amplification.Semantic proximity Read ↗

Visual detection of single-nucleotide polymorphism with hairpin oligonucleotide-functionalized gold nanoparticles.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.