Article
Matrix metalloproteinase-1 promoter genotypes and haplotypes are associated with carotid plaque presence.
Clinical biochemistry - 1 Nov 2012
Djurić Tamara, Stojković Ljiljana, Zivković Maja, Končar Igor, Stanković Aleksandra, Djordjević Ana, Alavantić Dragan
Abstract excerpt
OBJECTIVES: Matrix metalloproteinase (MMP)-1 degrades fibrillar collagens suggesting important role in vascular remodeling. Data about MMP-1 promoter polymorphisms and carotid atherosclerosis (CA) are scarce. The aim of this study was to evaluate association of MMP-1 genotypes/haplotypes with carotid plaque (CP) presence in Serbian population. DESIGN AND METHODS: Study enrolled a total of 702 participants: 274...
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