Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypermethylation of TFPI2 correlates with cervical cancer incidence in the Uygur and Han populations of Xinjiang, China.

International journal of clinical and experimental pathology - 1 Jan 2015

Dong Yuling, Tan Qiufen, Tao Lin, Pan Xiaolin, Pang Lijuan, Liang Weihua, Liu Wei, Zhang Wenjie, Li Feng, Jia Wei

Abstract excerpt

Tissue factor pathway inhibitor 2 (TFPI2) is a Kunitz-type serine proteinase inhibitor, which plays an important role in the etiology of human malignancies. DNA methylation is a common epigenetic modification of the genome that is involved in regulating many cellular processes. In addition to human papilloma virus (HPV) infection, DNA methylation may play a role in the carcinogenesis of cervical cancer....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma
Share to CpG Islands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Glycoproteins

Share to Incidence

Share to Neoplasm Invasiveness

Share to Uterine Cervical Dysplasia

Share to Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 25973077
PMCID: PMC4396244

Genes

TFPI2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypermethylation of TFPI2 correlates with cervical cancer incidence in the Uygur and Han populations of Xinjiang, China.PMID 25973077Read ↗

Tissue factor pathway inhibitor-2 was repressed by CpG hypermethylation through inhibition of KLF6 binding in highly invasive breast cancer cellsSemantic proximity Read ↗

The Role of Tissue Factor Pathway Inhibitor-2 in Cancer BiologySemantic proximity Read ↗

AGPAT Family in Cervical Cancer: A Multi-Omics Perspective on Prognosis and FunctionSemantic proximity Read ↗

Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Genetic association study of intron variants in the forkhead box protein P3 gene in Chinese patients diagnosed with cervical cancer.Semantic proximity Read ↗

IGSF4 promoter methylation and expression silencing in human cervical cancerSemantic proximity Read ↗

TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinomaSemantic proximity Read ↗

Reduced expression of tissue factor pathway inhibitor-2 contributes to apoptosis and angiogenesis in cervical cancerSemantic proximity Read ↗

Human Papillomavirus DNA Methylation as a Potential Biomarker for Cervical CancerSemantic proximity Read ↗

Methylation in the Promoters of <i>HS3ST2</i> and <i>CCNA1</i> Genes is Associated with Cervical Cancer in Uygur Women in XinjiangSemantic proximity Read ↗

Tissue factor pathway inhibitor-2 (TFPI-2)—an underappreciated partaker in cancer and metastasisSemantic proximity Read ↗

Genetic polymorphisms of PGF and TNFAIP2 genes related to cervical cancer risk among Uygur females from China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.