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Article

Sortase-mediated pilus fiber biogenesis in Streptococcus pneumoniae.

Structure (London, England : 1993) - 10 Dec 2008

Manzano Clothilde, Contreras-Martel Carlos, El Mortaji Lamya, Izoré Thierry, Fenel Daphna, Vernet Thierry, Schoehn Guy, Di Guilmi Anne Marie, Dessen Andréa

Abstract excerpt

Streptococcus pneumoniae is a piliated pathogen whose ability to circumvent vaccination and antibiotic treatment strategies is a cause of mortality worldwide. Pili play important roles in pneumococcal infection, but little is known about their biogenesis mechanism or the relationship between components of the pilus-forming machinery, which includes the fiber pilin (RrgB), two minor pilins (RrgA, RrgC), and three...

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Identifiers

PMID: 19081060
DOI: 10.1016/j.str.2008.10.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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