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Article

Group B Streptococcus pilus sortase regulation: a single mutation in the lid region induces pilin protein polymerization in vitro.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2013

Cozzi Roberta, Zerbini Francesca, Assfalg Michael, D'Onofrio Mariapina, Biagini Massimiliano, Martinelli Manuele, Nuccitelli Annalisa, Norais Nathalie, Telford John L, Maione Domenico, Rinaudo C Daniela

Abstract excerpt

Gram-positive bacteria build pili on their cell surface via a class C sortase-catalyzed transpeptidation mechanism from pilin protein substrates. Despite the availability of several crystal structures, pilus-related C sortases remain poorly characterized to date, and their mechanisms of transpept...

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PMID: 23631841
DOI: 10.1096/fj.13-227793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23631841-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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