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Full structure/function analysis of all the pilin subunits in a type 4 pilus: a complex of minor pilins in <i>Streptococcus sanguinis</i> mediates binding to glycans

2022-08-25

Abstract excerpt

Type 4 filaments (T4F) – of which type 4 pili (T4P) are the archetype – are a superfamily of filamentous nanomachines nearly ubiquitous in prokaryotes. T4F are polymers of one major pilin that also contain minor pilins whose roles are often poorly understood. Here, we complete the structure/function analysis of the full set of T4P pilins in the opportunistic pathogen Streptococcus sanguinis . We determined the st...

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Literature Corpus work
d0a7dd87-6818-5e49-82ec-356ba098ff6e
DOI
10.1101/2022.08.25.505150
Open publication

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Full structure/function analysis of all the pilin subunits in a type 4 pilus: a complex of minor pilins in <i>Streptococcus sanguinis</i> mediates binding to glycansDOI 10.1101/2022.08.25.505150
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