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Article

The relevance of CYSLTR1 gene polymorphism to the severity of allergic rhinitis and clinical responsiveness of montelukast in children.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Dec 2021

Zhao Miaomiao, Li Hao, Li Hui

Abstract excerpt

PURPOSE: The etiology of allergic rhinitis (AR) is closely correlated with the complex interactions between genetic and environmental factors. This study explored the effect of single-nucleotide polymorphisms (SNPs) of CYSLTR1 gene on the risk of AR and clinical response to montelukast treatment in children. METHODS: A total of 135 children with AR and 100 healthy children were included for subsequent analyses....

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PMID: 33837837
DOI: 10.1007/s00405-021-06771-z

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