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Article

The PPARGC1A Gly482Ser polymorphism is associated with left ventricular diastolic dysfunction in men.

BMC cardiovascular disorders - 11 Dec 2008

Ingelsson Erik, Bennet Louise, Ridderstråle Martin, Söderström Marianne, Råstam Lennart, Lindblad Ulf

Abstract excerpt

BACKGROUND: The Gly482Ser polymorphism in peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PPARGC1A) has been demonstrated to be associated with diabetes, obesity and hypertension, all of which are important risk factors for left ventricular diastolic dysfunction. METHODS: Th...

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Identifiers

PMID: 19077249
DOI: 10.1186/1471-2261-8-37
PMCID: PMC2637232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19077249-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The PPARGC1A Gly482Ser polymorphism is associated with left ventricular diastolic dysfunction in men.PMID 19077249Read ↗

Impact of the PPARGC1A Gly482Ser polymorphism on left ventricular structural and functional abnormalities in patients with hypertension.Semantic proximity Read ↗

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The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals.Semantic proximity Read ↗

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Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes.Semantic proximity Read ↗

PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites.Semantic proximity Read ↗

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Peroxisome proliferator-activated receptor-gamma coactivator-1 gene locus: associations with hypertension in middle-aged men.Semantic proximity Read ↗

Studies of the Gly482Ser polymorphism of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) gene in Danish subjects with the metabolic syndrome.Semantic proximity Read ↗

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