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Article

The PPARGC1A Gly482Ser polymorphism is associated with left ventricular diastolic dysfunction in men.

BMC cardiovascular disorders - 11 Dec 2008

Ingelsson Erik, Bennet Louise, Ridderstråle Martin, Söderström Marianne, Råstam Lennart, Lindblad Ulf

Abstract excerpt

BACKGROUND: The Gly482Ser polymorphism in peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PPARGC1A) has been demonstrated to be associated with diabetes, obesity and hypertension, all of which are important risk factors for left ventricular diastolic dysfunction. METHODS: The PPARGC1A Gly482Ser polymorphism was genotyped in a community-based cohort of 499 men and 533 women, who also...

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Identifiers

PMID: 19077249
DOI: 10.1186/1471-2261-8-37
PMCID: PMC2637232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The PPARGC1A Gly482Ser polymorphism is associated with left ventricular diastolic dysfunction in men.PMID 19077249Read ↗

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The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals.Semantic proximity Read ↗

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Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes.Semantic proximity Read ↗

PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites.Semantic proximity Read ↗

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