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Article

Increased risk of obesity associated with the variant allele of the PPARGC1A Gly482Ser polymorphism in physically inactive elderly men.

Diabetologia - 1 Mar 2006

Ridderstråle M, Johansson L E, Rastam L, Lindblad U

Abstract excerpt

AIMS/HYPOTHESIS: The variant allele of the Gly482Ser polymorphism in peroxisome proliferator-activated receptor-gamma co-activator-1alpha (PPARGC1A or PGC1alpha), a critical determinant of skeletal muscle metabolism, has been associated with obesity and type 2 diabetes. Previous studies indicate that these risks depend on sex and environmental triggers such as age. The aim of the present study was to investigate...

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PMID: 16474966
DOI: 10.1007/s00125-005-0129-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Increased risk of obesity associated with the variant allele of the PPARGC1A Gly482Ser polymorphism in physically inactive elderly men.PMID 16474966Read ↗

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Linking Metabolic Disease With the PGC-1α Gly482Ser Polymorphism.Semantic proximity Read ↗

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