Article
Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 2010
Lyashenko Natalia, Weissenböck Martina, Sharir Amnon, Erben Reinhold G, Minami Yasuhiro, Hartmann Christine
Abstract excerpt
Ror1 is a member of the Ror-family receptor tyrosine kinases. Ror1 is broadly expressed in various tissues and organs during mouse embryonic development. However, so far little is known about its function. The closely related family member Ror2 was shown to play a crucial role in skeletogenesis and has been shown to act as a co-receptor for Wnt5a mediating non-canonical Wnt-signaling. Previously, it has been...
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