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Article

Gastrin activates paracrine networks leading to induction of PAI-2 via MAZ and ASC-1.

American journal of physiology. Gastrointestinal and liver physiology - 1 Feb 2009

Almeida-Vega Simon, Catlow Krista, Kenny Susan, Dimaline Rod, Varro Andrea

Abstract excerpt

The gastric hormone gastrin regulates the expression of a variety of genes involved in control of acid secretion and also in the growth and organization of the gastric mucosa. One putative target is plasminogen activator inhibitor-2 (PAI-2), which is a component of the urokinase activator system that acts extracellularly to inhibit urokinase plasminogen activator (uPA) and intracellularly to suppress apoptosis....

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Source

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Identifiers

PMID: 19074642
DOI: 10.1152/ajpgi.90340.2008
PMCID: PMC2643906

Genes

MAZ
CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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