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Article

Upstream stimulatory factor regulates E box‐dependent PAI‐1 transcription in human epidermal keratinocytes

15 Sept 2004

Abstract excerpt

Certain growth factors (e.g., TGF-beta1) initiate a "plastic" response in human keratinocytes (HaCaT cells) characterized by changes in gene expression and increased cell motility. While microarray analyses identified a number of involved genes, plasminogen activator inhibitor type 1 (PAI-1) is among the subset most highly responsive to TGF-beta1. Previous antisense attenuation of PAI-1 synthesis confirmed an...

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PMID: 15372465
DOI: 10.1002/jcp.20211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Upstream stimulatory factor regulates E box‐dependent PAI‐1 transcription in human epidermal keratinocytesPMID 15372465Read ↗

Binding of upstream stimulatory factor 1 to the E-box regulates the 4G/5G polymorphism-dependent plasminogen activator inhibitor 1 expression in mast cells.Semantic proximity Read ↗

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Transcription factor PEA3 participates in the induction of urokinase plasminogen activator transcription in murine keratinocytes stimulated with epidermal growth factor or phorbol-ester.Semantic proximity Read ↗

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