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Helicobacter pylori Induces Antiapoptosis through Nuclear Factor–κB Activation

1 Dec 2003

Abstract excerpt

Although Helicobacter pylori is classified as a definite carcinogen, the mechanism underlying gastric carcinogenesis is not yet clear. We previously have shown that H. pylori activates an antiapoptotic gene, the cellular inhibitor of apoptosis protein 2 (c-IAP2), the underlying mechanism of which was investigated in the present study. cDNA array and real-time PCR analyses indicated that H. pylori showed a...

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PMID: 14639546
DOI: 10.1086/379629

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