Article
The NatA acetyltransferase couples Sup35 prion complexes to the [PSI+] phenotype.
Molecular biology of the cell - 1 Feb 2009
Pezza John A, Langseth Sara X, Raupp Yamamoto Rochele, Doris Stephen M, Ulin Samuel P, Salomon Arthur R, Serio Tricia R
Abstract excerpt
Protein-only (prion) epigenetic elements confer unique phenotypes by adopting alternate conformations that specify new traits. Given the conformational flexibility of prion proteins, protein-only inheritance requires efficient self-replication of the underlying conformation. To explore the cellular regulation of conformational self-replication and its phenotypic effects, we analyzed genetic interactions between...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
