The polymorphisms on Igkappa gene are related to susceptibility of breast cancer and gastric cancer.

doi:10.1089/gte.2008.0062

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The polymorphisms on Igkappa gene are related to susceptibility of breast cancer and gastric cancer.

Genetic testing - 1 Dec 2008

Hu Duosha, Tong Sun, Wei Ren, Hui Zheng, Haidan Liu, Zhi Duan, Lili Li, Wen Tan, Dan Zhao, Yanfeng Liu, Dongxin Lin, Ya Cao

Abstract excerpt

The phenomenon of immunoglobulin (Ig) expression in cancer cells has been discovered recently; the Ig protein expressed and secreted in cancer cells was found to be in favor of tumor growth. Two single-nucleotide polymorphism (SNP) loci rs232230 (5658C/G) and rs232228 (3635T/C) were identified on Igkappa gene previously, and we have demonstrated that they were associated with nasopharyngeal carcinoma...

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PMID: 19072568
DOI: 10.1089/gte.2008.0062

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