Article
Association of the variant rs2243421 of human DOC-2/DAB2 interactive protein gene (hDAB2IP) with gastric cancer in the Chinese Han population.
Gene - 15 Feb 2013
Xu Song, Zhou Yuan, Du Wei-Dong, Chen Gang, Zhou Fu-Sheng, Schneider Marion, Ma Xue-Ling, Xu Hong-Yuan, Zhang Xue-Jun
Abstract excerpt
Human DOC-2/DAB2 interactive protein (hDAB2IP) gene is a novel member of the Ras GTPase-activating family and has been demonstrated to be a tumor-suppressor gene that inhibits cell survival and proliferation and induces cell apoptosis. It was reported that the expression level of hDAB2IP in gastric cancer tissue was highly correlated with tumor progression, however, whether hDAB2IP genetic variants are associated...
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