Article
The role of HBV genotype, core promoter and precore mutations in advanced liver disease in renal transplant recipients.
Journal of hepatology - 1 Feb 2009
Tsai Ming-Chao, Chen Chien-Hung, Lee Chuan-Mo, Chen Yen-Ta, Chien Yu-Shu, Hung Chao-Hung, Wang Jing-Houng, Lu Sheng-Nan, Yen Yi-Hao, Changchien Chi-Sin, Hu Tsung-Hui
Abstract excerpt
BACKGROUND/AIMS: In renal transplant recipients (RTRs), chronic hepatitis B virus (HBV) infection may lead to poor outcomes. This study aimed to investigate the role of the HBV genotype, core promoter and precore mutations in advanced liver disease in RTRs. METHODS: We retrospectively reviewed 51 RTRs positive for hepatitis B surface antigen (HBsAg). HBV genotype determination and direct sequencing of core...
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