Article
Clinical significance of hepatitis B virus (HBV) genotypes and precore and core promoter mutations affecting HBV e antigen expression in Taiwan.
Journal of clinical microbiology - 1 Dec 2005
Chen Chien-Hung, Lee Chuan-Mo, Lu Sheng-Nan, Changchien Chi-Sin, Eng Hock-Liew, Huang Chao-Min, Wang Jing-Houng, Hung Chao-Hung, Hu Tsung-Hui
Abstract excerpt
To assess the prevalence and clinical significance of hepatitis B virus (HBV) genotypes and precore and core promoter mutations in Taiwan, a cohort of 200 Taiwanese chronic hepatitis B patients was analyzed. The HBV genotypes and sequences of the precore and the core promoter regions were determined in 66 asymptomatic carriers and 134 patients who had liver biopsy-verified chronic hepatitis and liver cirrhosis....
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