Article
Genome-wide analysis of membrane transport using yeast knockout arrays.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008
Burston Helen E, Davey Michael, Conibear Elizabeth
Abstract excerpt
The transport of membrane-bound proteins through post-Golgi compartments depends on the coordinated function of multiple genes that direct the recognition and routing of protein cargoes to their final cellular destination. As many of these sorting components are nonessential for viability, genome-wide screening of the yeast gene-deletion mutant collection provides a useful strategy for their identification. The...
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