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Article

The 5' regulatory region of the human fetal globin genes is a gene conversion hotspot.

Hemoglobin - 1 Jan 2008

Kalamaras Angelos, Chassanidis Christos, Samara Maria, Chiotoglou Ioanna, Vamvakopoulos Nikolaos K, Papadakis Manoussos N, Kollia Panagoula, Patrinos George P

Abstract excerpt

The human fetal globin genes consist of the first mammalian genomic loci for which gene conversion was reported. To date, 14 gene conversions have been described in the human Ggamma- and Agamma-globin genes, the vast majority of which are restricted to the coding sequences. Here, we provide evidence for three new gene conversion events in the 5' regulatory region of the human fetal globin genes, identified during...

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PMID: 19065335
DOI: 10.1080/03630260802507824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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