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Article

Translation of the Philadelphia chromosome into therapy for CML

8 Dec 2008

Abstract excerpt

Throughout its history, chronic myeloid leukemia (CML) has set precedents for cancer research and therapy. These range from the identification of the first specific chromosomal abnormality associated with cancer to the development of imatinib as a specific, targeted therapy for the disease. The successful development of imatinib as a therapeutic agent for CML can be attributed directly to decades of scientific...

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PMID: 19064740
DOI: 10.1182/blood-2008-07-077958

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